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In some embodiments, the otic formulation or composition comprises about 6% by weight of the viscosity modulating agent(s)

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In a mouse with obesity model, the activation of nuclear factor erythroid 2related factor 2 (Nrf2) by sulforaphane led to a reduction in obesity-related glomerulopathy and an increase in MT expression in podocyte cell cultures [131]

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[PUBMED Abstract] Ives NJ, Stowe RL, Lorigan P, et al.: Chemotherapy compared with biochemotherapy for the treatment of metastatic melanoma: a meta-analysis of 18 trials involving 2,621 patients